Resources

Supporting you from research to production

In this section, you can download protocols to support implementation in your workflow, along with publications and white papers to explore the underlying data in greater depth.

Need more documentation? We provide comprehensive regulatory support, including toxicology reports, documentation for regulatory submissions, a US Drug Master File (DMF), and GMP compliance certificates — all available upon request.

Publications

Ref 1: Svalgaard JD et al. Cell Transplantation, 2018 Sept; Vol 27(9): 1407-1412

Pentaisomaltose, An Alternative To DMSO. Engraftment Of Cryopreserved Human CD34+ Cells In Immunodeficient NSG Mice

Ref 2: Svalgaard JD et al. Transplantation and Cellular Engineering, 2016 May; Vol 56(5): 1088-1095

Low Molecular Weight Carbohydrate Pentaisomaltose May Replace Dimethyl Sulfoxide As A Safer Cryoprotectant For Cryopreservation Of Peripheral Blood Stem Cells

Ref 4: Haastrup EK et al. Transplantation and Apheresis Science, 2021; Vol 60(4): 103138

DMSO (Me2SO) Concentrations Of 1-2% In Combination With Pentaisomaltose Are Effective For Cryopreservation Of T Cells

Ref 5: Svalgaard JD et al. Cryobiology, 2020; Vol 96(01): 207-213

Cryopreservation Of Adipose Derived Stromal/Stem Cells Using 1–2% Me2SO (DMSO) In Combination With Pentaisomaltose: An Effective And Less Toxic Alternative To Comparable Freezing Media

Ref 8: Hamann A et al. Application Note, 2025 August

Superior Cryopreservation of T Cells in Low-DMSO, Animal-Origin-Free Formulation Using Optibumin 25 and PentaHibe Base

Protocols

Cryopreservation protocol using Pentahibe Complete

Protocol for DMSO-free cryopreservation of HPC(A) products

Protocol for DMSO-reduced cryopreservation using 10% Pentahibe Base, 2% DMSO and 4% albumin

Protocol for cryopreservation of gut biopsies using Pentahibe Complete

White Papers

Preserving Functional Performance of Human T Cells with PentaHibe Complete

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