Our Products
A natural carbohydrate-based cryoprotective agent offering proven efficacy with reduced toxicity compared to high concentrations of DMSO, Pentahibe® comes in a number of formulations to suit your needs.
PentaHibe®
Complete
Ready-to-use
Pentahibe® Complete is a ready-to-use cGMP compliant formulation that can be used with a range of cell types. With 10% pentaisomaltose and 2% DMSO as cryoprotective agents, Pentahibe® Complete significantly reduces DMSO-related toxicity and side effects.
- cGMP manufactured
- Reduced % of DMSO
- Sterile
- Serum-free
- Low endotoxins
- Water-like viscosity
Improved outcomes
Pentahibe® Complete, containing 2% DMSO, shows comparable results to commercially available cryosolutions with higher DMSO concentration and even demonstrates superior migratory potential.
Enhanced safety
Pentahibe® Complete, containing 2% DMSO, minimizes cellular toxicity and DMSO-related side effects, enhancing both safety and effectiveness vs. traditional DMSO-based cryopreservation methods.
Tested on several cell types
Pentahibe® Complete, cGMP manufactured, has been tested on T-cells, human mesenchymal stem cells, and CHO cells and comes with comprehensive documentation to support regulatory submissions.
PentaHibe®
Base
For further formulations
Pentahibe® Base (40% pentaisomaltose) is a natural, cGMP compliant, non-toxic cryoprotective agent that can be used as the sole cryoprotective agent or as a base for further formulations. In addition to offering complete flexibility, Pentahibe® Base can eliminate the need for DMSO or reduce the need for DMSO to 1-2%, which significantly lowers DMSO-related toxicity and side effects.
- 100% natural
- DMSO-free
- Xeno-free and animal component-free
- Protein-free
- Serum-free
0% DMSO for hematopoietic stem cells
DMSO-free Pentahibe® Base can be used as sole CPA for cryopreservation of hematopoietic stem cells and ensures the same recovery as with 10% DMSO
Same efficacy with only 1% DMSO for T cells
10% Pentahibe® Base and only 1% DMSO show similar viability and recovery to commercial formulations with 10% DMSO for cryopreservation of T cells
Robust safety profile
Preclinical and clinical studies confirm pentaisomaltose’s tolerability in both humans and various animal species, supported by comprehensive pharmaco-toxicological and clinical evidence.
- Products
- Data & Documents
- Contact
- Pharmacosmos A/S
- Roervangsvej 30
- DK-4300 Holbaek
- Denmark
- Tel: +45 5948 5959
- Email: pentahibe@pharmacosmos.com
- Business hours are Monday to Friday 08:00-16:00 CET